HSP90 INHIBITION DECREASES MITOCHONDRIAL PROTEIN TURNOVER.

Hsp90 inhibition decreases mitochondrial protein turnover.

Cells treated with hsp90 inhibitors exhibit pleiotropic changes, including an expansion of the mitochondrial compartment, accompanied by mitochondrial fragmentation and condensed mitochondrial morphology, with ultimate compromise of mitochondrial integrity and click here apoptosis.We identified several mitochondrial oxidative phosphorylation comple

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What Online User Innovation Communities Can Teach Us about Capturing the Experiences of Patients Living with Chronic Health Conditions. A Scoping Review.

BackgroundIn order to adapt to societal changes, healthcare systems need to switch from a disease orientation to a patient-centered approach.Virtual patient networks are a promising tool to favor this switch and much can be learned from the open and user innovation literature where the involvement of online user communities in the innovation proces

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Examining the Self-Harm and Suicide Contagion Effects of the Blue Whale Challenge on YouTube and Twitter: Qualitative Study

BackgroundResearch suggests that direct exposure to suicidal behaviors and acts of self-harm through social media may increase suicidality through imitation and modeling, particularly in more vulnerable populations.One example of a social media phenomenon that demonstrates how self-harming behavior could potentially be propagated is the blue whale

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